Napoli vs Pisa Prediction for 23 September 2025 - Football

What can we expect from the clash between Napoli and Pisa, which will wrap up the fourth round of the Italian championship? The match is set to take place at the Diego Armando Maradona Stadium. The Partenopei have kicked off the season in formidable fashion, winning all three of their opening Serie A fixtures and once again staking their claim for the title. Pisa, having just been promoted from Serie B, are still finding their footing at this new level, making their trip to Naples a daunting challenge.

Head-to-Head

The head-to-head history between Napoli and Pisa stretches back quite a while, with their last encounter taking place in 2007. Many years have passed since then, and the current matchup can be seen as an entirely new chapter, as almost everything has changed: the squads, the teams' levels, and their standing in Italian football.

Napoli Team Overview

Napoli, true to their status as reigning Serie A champions, have kicked off the new season with maximum confidence. The Partenopei have secured victories in all three of their opening matches, claiming the top spot in the table ahead of Juventus due to a superior goal difference.

In the last round, they delivered a statement performance away against Fiorentina. By the 50th minute, they were leading 3-0, and only then did they ease off, eventually finishing the match with a 3-1 victory. Even with this margin, the win was convincing and reinforced their status as strong title contenders. Yes, Napoli did suffer a 0-2 defeat to Manchester City in the Champions League after that match, but this loss shouldn't significantly impact their morale ahead of the upcoming clash. 

Pisa Team Overview

Pisa, having climbed to the top tier from Serie B, are struggling to adapt to the demands of the top division. Yes, they managed to pull off a surprise in the opening round by taking points off Atalanta (1-1), but things have taken a turn for the worse since then: they have suffered two consecutive defeats without scoring, and their attacking play looks severely limited.

Last weekend, Pisa fell at home to Udinese (0-1), failing to create many dangerous chances. Although they took 12 shots at goal, their xG amounted to just 0.50. If the team hopes to maintain their status in the top division, they need to take more risks against opponents of this caliber rather than sitting back in defense and relying on luck.

Latest news

Napoli

Antonio Conte, Napoli's head coach, admitted that the first-half sending-off significantly altered the game against Manchester City (0-2): "We had prepared for exactly this kind of start, and for the first 20 minutes, we played as planned. But the red card changed everything. I'm not here to judge whether the decision was right, but it's already challenging enough to play against City on equal terms." Despite the defeat, Conte found some positives: "Honestly, I felt we could have snatched some points. I'm pleased with the fighting spirit my players showed. I leave this match with positive feelings about our journey in Europe."

Napoli will be without at least three players. Goalkeeper Nikita Contini is sidelined with a hand fracture and is expected back by the end of October. Amir Rrahmani is recovering from a hamstring injury and should return by early October. The most significant absence remains Romelu Lukaku, who is out with a thigh injury and won't be available until mid-November.

Pisa

Alberto Gilardino, Pisa's coach, emphasized that his team deserved more in their match against Udinese (0-1): "The essence of the match is crystal clear. We started well and tried to control the game. However, in the final 25 meters, we lacked sharpness; we had six or seven chances to level the score." He also acknowledged the quality of the opposition and the need for further progress: "Runjaic is an excellent coach, and Udinese are a formidable team. My task is to get the most out of the players. It's part of the development journey, and some of them need to return to top form to make a difference."

Pisa's squad situation is somewhat simpler, but not without setbacks. Juan Cuadrado has a muscle injury and will return only by early October. The absence of such an experienced player limits their options on the flank, particularly in attacking play.

Goal Prediction

Goal Prediction

Napoli haven't been showcasing high-scoring football at home for quite some time: in 15 of their last 16 Serie A home games, they've scored no more than two goals. Most of this streak dates back to last season, clearly indicating that the Partenopei secured their victories not through blowouts, but by playing a balanced game and finding other ways to clinch wins. In the upcoming match, the scenario is unlikely to change—Pisa will likely play defensively and aim to be as cautious as possible, further reducing the chances of a goal fest from the hosts. We're backing Napoli to score under 1.5 goals.

Corner Prediction

At the start of the championship, Pisa's matches have been particularly favorable for those betting on a high number of corners. For instance, there were 14 corners in games against Udinese and Atalanta, with only the match against Roma slightly deviating from this pattern—there, the teams combined for just 8 corners. Napoli have also been consistent in this aspect: their matches almost always reach a total of 10 corners. In this scenario, we suggest going with over 9.5 corners.